Publications
& Resources

BRAIN HEALTH IMPACTS OF COVID-19

MAINSTREAM NEWS

A 'tsunami' of long COVID cases is about to hit, and some say the health-care system isn't ready

June 11, 2022 - Ottawa Citizen

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Long Covid is a ‘national crisis.’ So why are grants taking so long to get?

June 10, 2022 - Science

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How Effects on the Brain Can Produce Long COVID

April 26, 2022 - Yale News

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Long Covid-19 may remain a chronic condition for millions

April 6, 2022 - CNN

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Long COVID: The invisible public health crisis fuelling labour shortages

April 14, 2022 - Financial Post

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La galère financière des patients de la « COVID longue »

April 12, 2022 - Radio Canada

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Tulane study shows COVID-19’s lingering impacts on the brain

April 1, 2022 - Tulane News

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How long covid is accelerating a revolution in medical research

April 2, 2022 - Washington Post

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Memory and concentration problems are common in long COVID and must not be ignored, say scientists

March 17, 2022 - University of Cambridge

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Long covid could change the way researchers study chronic illness

March 16, 2022 - Washington Post

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Scans reveal how Covid may change the brain

March 7, 2022 - BBC News

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Almost a third of people report lingering symptom 6-12 months after COVID-19: study

March 4, 2022 - CTV News

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Researchers Are Getting Closer to Understanding Long COVID. But Treatments Are Likely Still a Ways Off

March 7, 2022 - Time

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Nerve damage may explain some cases of long COVID, U.S. study finds

March 1, 2022 - The Globe and Mail

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Que sait-on du syndrome post-COVID-19?

February  14, 2022 - Radio Canada

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Studies Identify Risk Factors for Long COVID

January 26, 2022 - The Scientist

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Thousands of Canadians may have acquired long-term impairment from COVID. They need support

February 27, 2022 - The Record

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The great gaslighting: how Covid longhaulers are still fighting for recognition

February 3, 2022 - The Guardian

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Toronto scientists are trying to crack one of COVID’s biggest mysteries: Its impact on the brain

January 30, 2022 - Toronto Star

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Long COVID will have health, economic impact for years to come, says expert Social Sharing

January 27, 2022 - CBC

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Even Mild COVID Infections Can Have Lasting Impacts Like ‘Chemo Brain,' Study Finds

January 11, 2022 - NBC New York

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When it comes to long COVID, the treatment playbook is constantly evolving

January 10, 2022 - CBC

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Chronic exhaustion, derailed lives and no way out. This is long COVID.

January 10, 2022 - Macleans's

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Everything we know about long COVID, from strange phantom smells to chronic fatigue

January 5, 2022 - National Post

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Why are they still sick? The latest clues in the mystery of COVID-19 long haulers

December 11, 2021 - Global News

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How COVID Might Sow Chaos in the Brain

November 10, 2021 - Scientific American

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Long covid: new wine in need of new bottles

November 9, 2021 - British Medical Journal

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Could long covid unlock clues to chronic fatigue and other poorly understood conditions?

November 7, 2021 - Washington Post

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Our social safety net is failing COVID-19 survivors

October 27, 2021 - Toronto Star

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The difficulties of estimating long Covid

September 26,  2021 - The Guardian

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Like polio, the long-term impact of COVID will be measured in disability

September 29,  2021 - CNN

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Post-illness symptoms like long Covid are probably more common than we think

September 12,  2021 - The Guardian

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Preliminary research finds that even mild cases of COVID-19 leave a mark on the brain – but it’s not yet clear how long it lasts

September 24,  2021 - The Conversation

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More than 150,000 people in Canada experience 'long COVID' symptoms, report estimates

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NIH builds large nationwide study population of tens of thousands to support research on long-term effects of COVID-19

September 15, 2021 - NIH News Release

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The long tail of COVID-19: Doctors, patients coming to grips with long COVID

September 8, 2021 - Ottawa Citizen

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Long Haulers are fighting for their future

September 1, 2021 - The Atlantic

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COVID-19 could serve as a 'Trojan horse' for dementia and Alzheimer's, experts say

August 31, 2021 - CTV News

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How does COVID-19 affect the brain? A troubling picture emerges.

August 18, 2021 - National Geographic

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How does COVID affect the brain? Two neuroscientists explain

August 10, 2021 - The Conversation

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The road to addressing Long Covid

July 30, 2021 - Science

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What Causes Long COVID Symptoms? NYU Langone Researchers Net $52 Million Federal Grant to Find Out

June 10, 2021 - NYU Langone Health News Hub

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COVID-19 affects men and women differently. So why don’t clinical trials report gender data?

July 6, 2021 - Science

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Long COVID and kids: scientists race to find answers

July 14, 2021 - Nature

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Doctors Worry That Memory Problems After COVID-19 May Set The Stage For Alzheimer's

July 26, 2021 - NPR News

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Brain fog to night sweats: Long COVID has more than 200 symptoms, study finds

July 15, 2021 - National Post

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COVID and the brain: researchers zero in on how damage occurs

July 7, 2021 - Nature

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A Tsunami of Disability Is Coming as a Result of ‘Long COVID’

July 6, 2021 - Scientific American

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Long COVID has exposed medicine's blind-spot

June 18, 2021 - The Lancet - Infectious Diseases

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Long Covid should be treated as disability, says TUC

 June 20, 2021 - The Guardian

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It’s Not Over ’Til It’s Over: Prevalence Of Long-Term Symptoms In Individuals Diagnosed With Covid-19

based on the following journal article:
Prevalence of long-term effects in individuals diagnosed with COVID-19: a living systematic review

June 15, 2021 - COVID-19 Immunity Task Force

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Study Documents Changes In Brain After Covid-19 Infection

June 20, 2021 - Forbes

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The Hidden Pandemic: Long Covid

JUNE 18, 2021 - Tony Blair Institute for Global Change

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Why are women more prone to long Covid?

June 13th, The Guardian

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Cleveland Clinic-led Study Identifies How COVID-19 Linked to Alzheimer’s Disease-like Cognitive Impairment

June 10th, 2021 - Cleveland Clinic Newsroom

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What Covid-19's long tail is revealing about disease

June 9th, BBC Future

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Scientists begin to unravel the mysteries of the coronavirus and brains

June 7th, 2021 - Washington Post

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Count the cost of disability caused by COVID-19

May 26, 2021 - Nature

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Understanding The Neurological And Psychological Effects Of Covid-19

April 29, 2021 - Forbes

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Researchers are closing in on long covid

May 1st, The Economist

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COVID-19 can affect the brain. New clues hint at how

April 27, 2021 - Science News

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Covid-19 gave scientists an opening to better understand how brain disorders arise

April 26, 2021 - Stat

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Une étude montréalaise pour mieux comprendre la COVID-19 longue

April 16, 2021 - Quebec Science

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A Close Look at How COVID-19 Infection Can Damage the Brain

April 15, 2021 - Brain and Behavior Research Foundation Blog

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How scientists are teasing apart the biology of Long COVID

April 13, 2021 - Science

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Psychiatric and neurological problems are common in COVID-19’s wake, study finds

April 8, 2021 - Los Angeles Times

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'Brain fog' and other neurologic symptoms can last for months after Covid

March 23, 2021 - NBC News

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Unlocking the Mysteries of Long COVID

April 2021 Issue - The Atlantic

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Long Covid isn’t as unique as we thought

March 11, 2021 - VOX

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In the wake of the pandemic: preparing for Long COVID (2021)

February 25, 2021 - WHO policy Brief

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COVID-19 Could Increase Dementia, Other Brain Disorders for Decades to Come

February 10, 2021 - Newsweek

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Time to team up and tackle Long Covid, says WHO expert

February 1, 2021 - France24

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Taking a Closer Look at COVID-19’s Effects on the Brain

January 14, 2021 - NIH Director's Blog

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COVID-19 long-haulers: Canada's forgotten patients

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COVID-19’s Effects on the Brain

January 20, 2021 - The Scientist

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What If You Never Get Better From Covid-19?

January 21, 2021 -  New York Times

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We're about to see a wave of long Covid. When will ministers take it seriously?

 January 21, 2021 - The Guardian

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One in 5 COVID-19 patients develop mental illness within 90 days -study

November 9, 2020 - Reuters

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Covid Survivors With Long-Term Symptoms Need Urgent Attention, Experts Say

December 4, 2020 - New York Times

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Pandemics Leave Us Forever Altered

June 2020 - The Atlantic

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Long after the fire of a Covid-19 infection, mental and neurological effects can still smolder

August 12, 2020 - Stat

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How coronavirus affects the brain

July 8, 2020 - The Conversation

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How Covid Attacks the brain

September 9, 2020 - New York Times

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'I Feel Like I Have Dementia’: Brain Fog Plagues Covid Survivors.

October 11, 2020 - New York Times

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How COVID-19 Can Damage the Brain

September 15, 2020 - Nature

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How COVID-19 Attacks the Brain

November 1, 2020 - Monitor on Psychology

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EXTERNAL SCIENTIFIC LITERATURE

Drugmakers, scientists begin the hunt for long COVID treatments

March 25, 2022 - CTV News

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Global Prevalence of Post-Acute Sequelae of COVID-19 (PASC) or Long COVID: A Meta-Analysis and Systematic Review

Chen Chen, Spencer R. Haupert, Lauren Zimmermann, Xu Shi, Lars G. Fritsche, Bhramar Mukherjee. medRxiv 2021.11.15.21266377; doi: https://doi.org/10.1101/2021.11.15.21266377

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Almost a third of people report lingering symptom 6-12 months after COVID-19: study

March 4, 2022 - CTV News

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Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP).

Horn A. et al. Infection. October 12, 2021.

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Assessment of Cognitive Function in Patients After COVID-19 Infection

Becker, J. JAMA Network Open. October 22, 2021

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Long-COVID: neurological manifestations and management

Williams, S. et al. Journal of Neurology. October 11, 2021

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Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection

Groff, D et al. JAMA Network Open. October 13, 2021

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Acute and post-acute neurological manifestations of COVID-19: present findings, critical appraisal, and future directions

Beghi, E. Journal of Neurology. October 21, 2021.

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A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene

Magusali, N et al. Brain. October 7, 2021.

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Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19

Taquet, M et al. Plos Medicine. September 28, 2021

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Implications of Innate Immunity in Post-Acute Sequelae of Non-Persistent Viral Infections

Sparrer et A. Cells. August 19, 2021

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More than 50 long-term effects of COVID-19: a systematic review and meta-analysis

Villapol S. Et al. Scientific Reports. August 9, 2021.

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Neuro-COVID long-haulers exhibit broad dysfunction in T cell memory generation and responses to vaccination

Visvabharathy L. et al. medRxiv. August 9, 2021.

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Post-viral effects of COVID-19 in the olfactory system and their implications

Xydakis. M et al. The Lancet Neurology. July 30, 2021.

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SARS-CoV-2 Susceptibility and COVID-19 Mortality Among Older Adults With Cognitive Impairment: Cross-Sectional Analysis From Hospital Records in a Diverse US Metropolitan Area

Pan. A et al. Frontiers in Neurology. July 22, 2021.

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Cognitive deficits in people who have recovered from COVID-19.

Hampshire, R. et al. Eclinical Medicine. July 22, 2021.

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Characterizing long COVID in an international cohort: 7 months of symptoms and their impact Hannah E. Davis 1

Davis, H et al. Eclinical Medicine. July 15, 2021

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Burden of post-COVID-19 syndrome and implications for healthcare service planning: A population-based cohort study

Menges, D et al. PLoS One. July 12, 2021

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Unraveling the Mystery Surrounding Post-Acute Sequelae of COVID-19

Ramakrishnan, R et al. Frontiers in Immunology. June 30, 2021.


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Hospital-treated infectious diseases and the risk of dementia: a large, multicohort, observational study with a replication cohort

Sipila, P et al. The Lancet Infectious Diseases. June 21, 2021

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The Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 infection

Moghimi, Narges et al. “The Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 infection.” Current neurology and neuroscience reports vol. 21,9 44. 28 Jun. 2021, doi:10.1007/s11910-021-01130-1

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Brain imaging before and after COVID-19 in UK Biobank

Gwenaëlle Douaud, Soojin Lee, Fidel Alfaro-Almagro, Christoph Arthofer, Chaoyue Wang, Frederik Lange, Jesper L.R. Andersson, Ludovica Griffanti, Eugene Duff, Saad Jbabdi, Bernd Taschler, Anderson Winkler, Thomas E. Nichols, Rory Collins, Paul M. Matthews, Naomi Allen, Karla L. Miller, Stephen M. Smith

medRxiv June 11, 2021; doi: https://doi.org/10.1101/2021.06.11.21258690

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Prevalence of long-term effects in individuals diagnosed with COVID-19: a living systematic review

Francesca Reyes Domingo, Lisa A Waddell, Angela M. Cheung, Curtis L. Cooper, Veronica J. Belcourt, Alexandra M. E. Zuckermann, Tricia Corrin, Rukshanda Ahmad, Laura Boland, Claudie Laprise, Leanne Idzerda, Anam Khan, Alejandra Jaramillo Garcia

medRxiv, June 2, 2021; doi: https://doi.org/10.1101/2021.06.03.21258317

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Attributes and predictors of long COVID

Sudre, C.H., Murray, B., Varsavsky, T. et al. Attributes and predictors of long COVID. Nat Med 27, 626–631 (2021).

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Approaches to understanding COVID‐19 and its neurological associations

Beghi, E., Michael, B., Solomon, T., Westenberg, E., Winkler, A. Annals of Neurology. April 9, 2021.
doi: 10.1002/ana.26076.

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6-month neurological and psychiatric outcomes in 236,379 survivors of COVID-19: a retrospective cohort study using electronic health records

Taquet, M., Geddes JR, Husain, M., Luciano, S., Harrison, PJ. The Lancet. April 06, 2021.

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Post-acute COVID-19 syndrome

Nalbandian, A., Sehgal, K., Gupta, A. et al. 2021. Nature Medicine. https://doi.org/10.1038/s41591-021-01283-z

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Neurological infection with SARS-CoV-2 — the story so far

Solomon, T. Nat Rev Neurol 17, 65–66 (2021). https://doi.org/10.1038/s41582-020-00453-w

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The chronic neuropsychiatric sequelae of COVID‐19: The need for a prospective study of viral impact on brain functioning

de Erausquin, GA, Snyder, H, Carrillo, M, et al. Alzheimer's Dement. 2021; 1– 9.

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NeuroCOVID: it's time to join forces globally

Helbok, R., Chou, S., Beghi, E., Mainali, S., Frontera, J., Robertson, C., Fink, E., Schober, M., Moro, E., McNett, M. and Bassetti, C., 2021. The Lancet Neurology.

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Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62,354 COVID-19 cases in the USA

Taquet, M., Luciano, S., Geddes, J. and Harrison, P., 2021. Lancet Psychiatry.

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A systematic review of neurological symptoms and complications of COVID-19

Chen X, Laurent S, Onur OA, et al. J Neurol. 2020;1-11. doi:10.1007/s00415-020-10067-3

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Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019: A Review

Zubair AS, McAlpine LS, Gardin T, Farhadian S, Kuruvilla DE, Spudich S. JAMA Neurol. Published online May 29, 2020. doi:10.1001/jamaneurol.2020.2065

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Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

Mao L, Jin H, Wang M, et al.  JAMA Neurol. 2020;77(6):683–690. doi:10.1001/jamaneurol.2020.1127

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SARS-CoV-2: Olfaction, Brain Infection, and the Urgent Need for Clinical Samples Allowing Earlier Virus Detection.

Butowt R, Bilinska K. ACS Chem Neurosci. 2020;11(9):1200-1203. doi:10.1021/acschemneuro.0c00172

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Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science.

Holmes, Emily A et al. The Lancet Psychiatry, Volume 7, Issue 6, 547 – 560

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Frequency of neurological manifestations in COVID-19: a systematic review and meta-analysis of 350 studies.

Misra, S. et al. Preprint. medRxiv. April 23, 2021. https://doi.org/10.1101/2021.04.20.21255780

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High-dimensional characterization of post-acute sequalae of COVID-19

Al-Aly, Z., Xie, Y. Bowe, B. Nature. April 22, 2021

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ORGANIZATIONS OF INTEREST

Long-COVID Alliance

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COVID Long Haulers Support Group Canada

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International Severe Acute Respiratory and Emerging Infection Consortium

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Survivor Corps

A grassroots organization to connect and mobilize COVID-19 survivors to engage in research studies to further our understanding of long-term effects of the disease. 

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Brain Infections Global

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ADDITIONAL SARS-COV-2 LITERATURE RESOURCES

Journal of Neurology, Neurosurgery, and Neuropsychiatry COVID-19 blog

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COVID-19 Literature Surveillance Team

 

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LIT COVID

 

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Viruses and the Brain

Major advances in neuroinfectious diseases in the past two decades

April 2022, Nature

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Can we vaccinate against Epstein-Barr, the virus you didn’t know you had?

March 20, 2022 - The Guardian

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Analysis: Future infectious diseases: Recent history shows we can never again be complacent about pathogens

March 2, 2022 -  Brighter World

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The Puzzling Virus That Infects Almost Everyone

March 3, 2022 - The Atlantic

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How past pandemics may have caused Parkinson's

January 31, 2022 - BBC Future

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Epstein-Barr Virus Found to Trigger Multiple Sclerosis

Scientific American - January 13, 2022 - 

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Study Links Flu to Increased Parkinson’s Risk a Decade Later

The Scientist - November 19, 2021

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Multiple sclerosis: the link with earlier infection just got stronger – new study

The Conversation - October 11, 2021.

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Alzheimer's: The heretical and hopeful role of infection

BBC Future - October 6th, 2021

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New evidence shows how viral infections could promote Alzheimer’s

New Atlas - October 19, 2021.

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How pandemics strengthen links between viruses and autoimmunity

Nature - July 14, 2021

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Parkinson’s strikes more men than women. Researchers have worked for decades to learn why

Washington Post - July 4, 2021

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Environmental impacts on brain health

Mental health and Climate Change: Policy Brief

June 3, 2022 - World Health Organization

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How Does the Health of Our Planet Affect Our Own Health?

April 4, 2022 - News Medical Life Sciences

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One Health is critical to addressing zoonotic public health threats and environmental issues

March 21, 2022 - World Health Organization

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From concept to action: a united, holistic and One Health approach to respond to the climate change crisis

February 10, 2022 - Infectious Diseases of Poverty

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Health Canada report on climate change is dire, but not hopeless

February 14, 2022 - The Montreal Gazette

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Climate change: Five things we've learned from the IPCC report

March 1, 2022 - BBC News

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Zoonotic disease: Explained 

February 2, 2022 - Wellcome Foundation

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How a Record-Breaking Heat Wave Fueled Climate Anxiety

January 28, 2022 - Scientific American

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Pandemic underscores importance of better brain health

January 6, 2022 - Toronto Star

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Air Pollution May Cancel Out Benefits of Exercise On Brain Health

December 14, 2021 - Futurity

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Pandemic Preparedness

Les changements climatiques risquent de provoquer une multiplication des pandémies

June 5, 2022 - Radio- Canada

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Ontario doctors speak up about the need to plan and prepare for future pandemics

March 21, 2022 - Toronto Star

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How should the world respond to the next pandemic?

March 18 - The Guardian

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An ounce of pandemic prevention is worth a pound of cure

March 1, 2022 - The Lancet Microbe

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Health groups urge greater funding to combat future pandemic

March 7, 2022 - Financial Times

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Harnessing technology for pandemic preparedness demands system reform

February 18, 2022 - Brookings Institute

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Failure to prevent pandemics at source is ‘greatest folly’, say scientists

February 4, 2022 - The Guardian

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One Health: A crucial approach to preventing and preparing for future pandemics

December 23, 2021 - The Conversation

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2021 Global Health Security Index - Advancing Collective action and accountability amid global crisis

December 8, 2021

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World Health Assembly agrees to launch process to develop historic global accord on pandemic prevention, preparedness and response

December 1, 2021 - WHO

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Preventing future pandemics starts with recognizing links between human and animal health

November 3, 2021 - The Conversation

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One Health as a Pillar for a Transformative Pandemic Treaty

Policy Brief developed by Global Health Centre, Graduate Institute of International and Development Studies, Geneva.

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We’re Already Barreling Toward the Next Pandemic

September 29,  2021 - The Atlantic

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Has COVID taught us anything about pandemic preparedness?

Nature - August 13, 2021

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