Publications
& Resources
BRAIN HEALTH IMPACTS OF COVID-19
MAINSTREAM NEWS
February 29, 2024
Leaders call for scale-up in implementing One Health approach
February 29th. 2024 - World Health Organization news release
December 8, 2023
Experiences of Canadians with long-term symptoms following COVID-19
December 8th, 2023 - Statistics Canada
December 3, 2023
Joint statement from the Minister of Health, the Minister of the Environment and Climate Change and the Minister of Indigenous Services on COP28
December 3rd, 2023 - Health Canada news release
June 1, 2023
Canadian researchers find brain inflammation in patients with long COVID
June 1, 2023 - CTV News
March 13, 2023
The knowns — and known unknowns — of long Covid, explained
March 13, 2023 - VOX
How “long covid” is shedding light on postviral syndromes
September 21, 2022 - British Medical Journal
At least 17 million people in the WHO European Region experienced long COVID in the first two years of the pandemic; millions may have to live with it for years to come
September 13, 2022 - World Health Organization
Long COVID Experts and Advocates Say the Government Is Ignoring 'the Greatest Mass-Disabling Event in Human History'
September 19, 2022 - Time
SARS-CoV-2 Hijacks nanotubes between neurons to infect them
July 21, 2022 - Institut Pasteur
Women have a higher chance of developing long COVID than men, study finds
June 25, 2022 - CTV News
A 'tsunami' of long COVID cases is about to hit, and some say the health-care system isn't ready
June 11, 2022 - Ottawa Citizen
Long Covid is a ‘national crisis.’ So why are grants taking so long to get?
June 10, 2022 - Science
Long COVID: The invisible public health crisis fuelling labour shortages
April 14, 2022 - Financial Post
How long covid is accelerating a revolution in medical research
April 2, 2022 - Washington Post
Memory and concentration problems are common in long COVID and must not be ignored, say scientists
March 17, 2022 - University of Cambridge
Long covid could change the way researchers study chronic illness
March 16, 2022 - Washington Post
Almost a third of people report lingering symptom 6-12 months after COVID-19: study
March 4, 2022 - CTV News
Researchers Are Getting Closer to Understanding Long COVID. But Treatments Are Likely Still a Ways Off
March 7, 2022 - Time
Nerve damage may explain some cases of long COVID, U.S. study finds
March 1, 2022 - The Globe and Mail
Thousands of Canadians may have acquired long-term impairment from COVID. They need support
February 27, 2022 - The Record
The great gaslighting: how Covid longhaulers are still fighting for recognition
February 3, 2022 - The Guardian
Toronto scientists are trying to crack one of COVID’s biggest mysteries: Its impact on the brain
January 30, 2022 - Toronto Star
Long COVID will have health, economic impact for years to come, says expert Social Sharing
January 27, 2022 - CBC
Even Mild COVID Infections Can Have Lasting Impacts Like ‘Chemo Brain,' Study Finds
January 11, 2022 - NBC New York
When it comes to long COVID, the treatment playbook is constantly evolving
January 10, 2022 - CBC
Chronic exhaustion, derailed lives and no way out. This is long COVID.
January 10, 2022 - Macleans's
Everything we know about long COVID, from strange phantom smells to chronic fatigue
January 5, 2022 - National Post
Why are they still sick? The latest clues in the mystery of COVID-19 long haulers
December 11, 2021 - Global News
Could long covid unlock clues to chronic fatigue and other poorly understood conditions?
November 7, 2021 - Washington Post
Like polio, the long-term impact of COVID will be measured in disability
September 29, 2021 - CNN
Post-illness symptoms like long Covid are probably more common than we think
September 12, 2021 - The Guardian
Preliminary research finds that even mild cases of COVID-19 leave a mark on the brain – but it’s not yet clear how long it lasts
September 24, 2021 - The Conversation
More than 150,000 people in Canada experience 'long COVID' symptoms, report estimates
September 15 - CBC News
Related report - Understanding the Post COVID-19 Condition (Long COVID) and the Expected Burden for Ontario
NIH builds large nationwide study population of tens of thousands to support research on long-term effects of COVID-19
September 15, 2021 - NIH News Release
The long tail of COVID-19: Doctors, patients coming to grips with long COVID
September 8, 2021 - Ottawa Citizen
COVID-19 could serve as a 'Trojan horse' for dementia and Alzheimer's, experts say
August 31, 2021 - CTV News
How does COVID-19 affect the brain? A troubling picture emerges.
August 18, 2021 - National Geographic
How does COVID affect the brain? Two neuroscientists explain
August 10, 2021 - The Conversation
What Causes Long COVID Symptoms? NYU Langone Researchers Net $52 Million Federal Grant to Find Out
June 10, 2021 - NYU Langone Health News Hub
COVID-19 affects men and women differently. So why don’t clinical trials report gender data?
July 6, 2021 - Science
Doctors Worry That Memory Problems After COVID-19 May Set The Stage For Alzheimer's
July 26, 2021 - NPR News
Brain fog to night sweats: Long COVID has more than 200 symptoms, study finds
July 15, 2021 - National Post
A Tsunami of Disability Is Coming as a Result of ‘Long COVID’
July 6, 2021 - Scientific American
Long COVID has exposed medicine's blind-spot
June 18, 2021 - The Lancet - Infectious Diseases
It’s Not Over ’Til It’s Over: Prevalence Of Long-Term Symptoms In Individuals Diagnosed With Covid-19
based on the following journal article:
Prevalence of long-term effects in individuals diagnosed with COVID-19: a living systematic review
June 15, 2021 - COVID-19 Immunity Task Force
Cleveland Clinic-led Study Identifies How COVID-19 Linked to Alzheimer’s Disease-like Cognitive Impairment
June 10th, 2021 - Cleveland Clinic Newsroom
Scientists begin to unravel the mysteries of the coronavirus and brains
June 7th, 2021 - Washington Post
Understanding The Neurological And Psychological Effects Of Covid-19
April 29, 2021 - Forbes
Covid-19 gave scientists an opening to better understand how brain disorders arise
April 26, 2021 - Stat
Une étude montréalaise pour mieux comprendre la COVID-19 longue
April 16, 2021 - Quebec Science
A Close Look at How COVID-19 Infection Can Damage the Brain
April 15, 2021 - Brain and Behavior Research Foundation Blog
Psychiatric and neurological problems are common in COVID-19’s wake, study finds
April 8, 2021 - Los Angeles Times
'Brain fog' and other neurologic symptoms can last for months after Covid
March 23, 2021 - NBC News
In the wake of the pandemic: preparing for Long COVID (2021)
February 25, 2021 - WHO policy Brief
COVID-19 Could Increase Dementia, Other Brain Disorders for Decades to Come
February 10, 2021 - Newsweek
Taking a Closer Look at COVID-19’s Effects on the Brain
January 14, 2021 - NIH Director's Blog
COVID-19 long-haulers: Canada's forgotten patients
January 23, 2021 - CBC Marketplace
Related Article: 60% of COVID-19 long-haulers say government is 'absolutely ignoring them,' Marketplace questionnaire finds. CBC
We're about to see a wave of long Covid. When will ministers take it seriously?
January 21, 2021 - The Guardian
One in 5 COVID-19 patients develop mental illness within 90 days -study
November 9, 2020 - Reuters
Covid Survivors With Long-Term Symptoms Need Urgent Attention, Experts Say
December 4, 2020 - New York Times
Long after the fire of a Covid-19 infection, mental and neurological effects can still smolder
August 12, 2020 - Stat
'I Feel Like I Have Dementia’: Brain Fog Plagues Covid Survivors.
October 11, 2020 - New York Times
EXTERNAL SCIENTIFIC LITERATURE
January 13, 2023
Long COVID: major findings, mechanisms and recommendations
January 13, 2023 - Nature Reviews Microbiology
Long-term neurologic outcomes of COVID-19
Xu, E., Xie, Y. & Al-Aly, Z. Nat Med (2022). https://doi.org/10.1038/s41591-022-02001-z
Global Prevalence of Post-Acute Sequelae of COVID-19 (PASC) or Long COVID: A Meta-Analysis and Systematic Review
Chen Chen, Spencer R. Haupert, Lauren Zimmermann, Xu Shi, Lars G. Fritsche, Bhramar Mukherjee. medRxiv 2021.11.15.21266377; doi: https://doi.org/10.1101/2021.11.15.21266377
Almost a third of people report lingering symptom 6-12 months after COVID-19: study
March 4, 2022 - CTV News
Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP).
Horn A. et al. Infection. October 12, 2021.
Assessment of Cognitive Function in Patients After COVID-19 Infection
Becker, J. JAMA Network Open. October 22, 2021
Long-COVID: neurological manifestations and management
Williams, S. et al. Journal of Neurology. October 11, 2021
Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection
Groff, D et al. JAMA Network Open. October 13, 2021
Acute and post-acute neurological manifestations of COVID-19: present findings, critical appraisal, and future directions
Beghi, E. Journal of Neurology. October 21, 2021.
A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene
Magusali, N et al. Brain. October 7, 2021.
Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19
Taquet, M et al. Plos Medicine. September 28, 2021
Implications of Innate Immunity in Post-Acute Sequelae of Non-Persistent Viral Infections
Sparrer et A. Cells. August 19, 2021
More than 50 long-term effects of COVID-19: a systematic review and meta-analysis
Villapol S. Et al. Scientific Reports. August 9, 2021.
Neuro-COVID long-haulers exhibit broad dysfunction in T cell memory generation and responses to vaccination
Visvabharathy L. et al. medRxiv. August 9, 2021.
Post-viral effects of COVID-19 in the olfactory system and their implications
Xydakis. M et al. The Lancet Neurology. July 30, 2021.
SARS-CoV-2 Susceptibility and COVID-19 Mortality Among Older Adults With Cognitive Impairment: Cross-Sectional Analysis From Hospital Records in a Diverse US Metropolitan Area
Pan. A et al. Frontiers in Neurology. July 22, 2021.
Cognitive deficits in people who have recovered from COVID-19.
Hampshire, R. et al. Eclinical Medicine. July 22, 2021.
Characterizing long COVID in an international cohort: 7 months of symptoms and their impact Hannah E. Davis 1
Davis, H et al. Eclinical Medicine. July 15, 2021
Burden of post-COVID-19 syndrome and implications for healthcare service planning: A population-based cohort study
Menges, D et al. PLoS One. July 12, 2021
Unraveling the Mystery Surrounding Post-Acute Sequelae of COVID-19
Ramakrishnan, R et al. Frontiers in Immunology. June 30, 2021.
Hospital-treated infectious diseases and the risk of dementia: a large, multicohort, observational study with a replication cohort
Sipila, P et al. The Lancet Infectious Diseases. June 21, 2021
The Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 infection
Moghimi, Narges et al. “The Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 infection.” Current neurology and neuroscience reports vol. 21,9 44. 28 Jun. 2021, doi:10.1007/s11910-021-01130-1
Brain imaging before and after COVID-19 in UK Biobank
Gwenaëlle Douaud, Soojin Lee, Fidel Alfaro-Almagro, Christoph Arthofer, Chaoyue Wang, Frederik Lange, Jesper L.R. Andersson, Ludovica Griffanti, Eugene Duff, Saad Jbabdi, Bernd Taschler, Anderson Winkler, Thomas E. Nichols, Rory Collins, Paul M. Matthews, Naomi Allen, Karla L. Miller, Stephen M. Smith
medRxiv June 11, 2021; doi: https://doi.org/10.1101/2021.06.11.21258690
Prevalence of long-term effects in individuals diagnosed with COVID-19: a living systematic review
Francesca Reyes Domingo, Lisa A Waddell, Angela M. Cheung, Curtis L. Cooper, Veronica J. Belcourt, Alexandra M. E. Zuckermann, Tricia Corrin, Rukshanda Ahmad, Laura Boland, Claudie Laprise, Leanne Idzerda, Anam Khan, Alejandra Jaramillo Garcia
medRxiv, June 2, 2021; doi: https://doi.org/10.1101/2021.06.03.21258317
Attributes and predictors of long COVID
Sudre, C.H., Murray, B., Varsavsky, T. et al. Attributes and predictors of long COVID. Nat Med 27, 626–631 (2021).
Approaches to understanding COVID‐19 and its neurological associations
Beghi, E., Michael, B., Solomon, T., Westenberg, E., Winkler, A. Annals of Neurology. April 9, 2021.
doi: 10.1002/ana.26076.
6-month neurological and psychiatric outcomes in 236,379 survivors of COVID-19: a retrospective cohort study using electronic health records
LEARN MOREPost-acute COVID-19 syndrome
Nalbandian, A., Sehgal, K., Gupta, A. et al. 2021. Nature Medicine. https://doi.org/10.1038/s41591-021-01283-z
Neurological infection with SARS-CoV-2 — the story so far
Solomon, T. Nat Rev Neurol 17, 65–66 (2021). https://doi.org/10.1038/s41582-020-00453-w
The chronic neuropsychiatric sequelae of COVID‐19: The need for a prospective study of viral impact on brain functioning
LEARN MORENeuroCOVID: it's time to join forces globally
Helbok, R., Chou, S., Beghi, E., Mainali, S., Frontera, J., Robertson, C., Fink, E., Schober, M., Moro, E., McNett, M. and Bassetti, C., 2021. The Lancet Neurology.
Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62,354 COVID-19 cases in the USA
LEARN MOREA systematic review of neurological symptoms and complications of COVID-19
Chen X, Laurent S, Onur OA, et al. J Neurol. 2020;1-11. doi:10.1007/s00415-020-10067-3
Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019: A Review
Zubair AS, McAlpine LS, Gardin T, Farhadian S, Kuruvilla DE, Spudich S. JAMA Neurol. Published online May 29, 2020. doi:10.1001/jamaneurol.2020.2065
Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China
Mao L, Jin H, Wang M, et al. JAMA Neurol. 2020;77(6):683–690. doi:10.1001/jamaneurol.2020.1127
SARS-CoV-2: Olfaction, Brain Infection, and the Urgent Need for Clinical Samples Allowing Earlier Virus Detection.
Butowt R, Bilinska K. ACS Chem Neurosci. 2020;11(9):1200-1203. doi:10.1021/acschemneuro.0c00172
Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science.
Holmes, Emily A et al. The Lancet Psychiatry, Volume 7, Issue 6, 547 – 560
Frequency of neurological manifestations in COVID-19: a systematic review and meta-analysis of 350 studies.
Misra, S. et al. Preprint. medRxiv. April 23, 2021. https://doi.org/10.1101/2021.04.20.21255780
High-dimensional characterization of post-acute sequalae of COVID-19
Al-Aly, Z., Xie, Y. Bowe, B. Nature. April 22, 2021
ORGANIZATIONS OF INTEREST
Long-COVID Alliance
LEARN MORECOVID Long Haulers Support Group Canada
LEARN MOREInternational Severe Acute Respiratory and Emerging Infection Consortium
LEARN MORESurvivor Corps
A grassroots organization to connect and mobilize COVID-19 survivors to engage in research studies to further our understanding of long-term effects of the disease.
Brain Infections Global
LEARN MOREADDITIONAL SARS-COV-2 LITERATURE RESOURCES
Viruses and the Brain
Can we vaccinate against Epstein-Barr, the virus you didn’t know you had?
March 20, 2022 - The Guardian
Analysis: Future infectious diseases: Recent history shows we can never again be complacent about pathogens
March 2, 2022 - Brighter World
Epstein-Barr Virus Found to Trigger Multiple Sclerosis
Scientific American - January 13, 2022 -
Study Links Flu to Increased Parkinson’s Risk a Decade Later
The Scientist - November 19, 2021
Multiple sclerosis: the link with earlier infection just got stronger – new study
The Conversation - October 11, 2021.
New evidence shows how viral infections could promote Alzheimer’s
New Atlas - October 19, 2021.
Parkinson’s strikes more men than women. Researchers have worked for decades to learn why
Washington Post - July 4, 2021
Environmental impacts on brain health
Les changements climatiques risquent de provoquer une multiplication des pandémies
June 5, 2022 - Radio- Canada
How Does the Health of Our Planet Affect Our Own Health?
April 4, 2022 - News Medical Life Sciences
One Health is critical to addressing zoonotic public health threats and environmental issues
March 21, 2022 - World Health Organization
From concept to action: a united, holistic and One Health approach to respond to the climate change crisis
February 10, 2022 - Infectious Diseases of Poverty
Health Canada report on climate change is dire, but not hopeless
February 14, 2022 - The Montreal Gazette
How a Record-Breaking Heat Wave Fueled Climate Anxiety
January 28, 2022 - Scientific American
Air Pollution May Cancel Out Benefits of Exercise On Brain Health
December 14, 2021 - Futurity
Pandemic Preparedness
After the pandemic — Canada must boost research funding to safeguard our future health
June 16, 2022 - Ottawa Citizen
Les changements climatiques risquent de provoquer une multiplication des pandémies
June 5, 2022 - Radio- Canada
Ontario doctors speak up about the need to plan and prepare for future pandemics
March 21, 2022 - Toronto Star
An ounce of pandemic prevention is worth a pound of cure
March 1, 2022 - The Lancet Microbe
Health groups urge greater funding to combat future pandemic
March 7, 2022 - Financial Times
Harnessing technology for pandemic preparedness demands system reform
February 18, 2022 - Brookings Institute
Failure to prevent pandemics at source is ‘greatest folly’, say scientists
February 4, 2022 - The Guardian
One Health: A crucial approach to preventing and preparing for future pandemics
December 23, 2021 - The Conversation
2021 Global Health Security Index - Advancing Collective action and accountability amid global crisis
December 8, 2021
World Health Assembly agrees to launch process to develop historic global accord on pandemic prevention, preparedness and response
December 1, 2021 - WHO
Preventing future pandemics starts with recognizing links between human and animal health
November 3, 2021 - The Conversation
One Health as a Pillar for a Transformative Pandemic Treaty
Policy Brief developed by Global Health Centre, Graduate Institute of International and Development Studies, Geneva.